Cloudflare makes Python Workers generally available with framework and Hyperdrive support
After a two-year preview, Cloudflare now treats Python as a first-class supported Workers language, with native platform bindings, WSGI and ASGI connectors, and socket support for database drivers through Hyperdrive. The runtime still uses Pyodide inside WebAssembly, so packages with native extensions need WebAssembly-compatible builds and the package ecosystem remains a practical constraint.